Lipodissolve

Lipodissolve | Mesotherapy

Mesotherapy or lipodissolve is not performed at Dr. J. J. Wendel Plastic Surgery.

Lipodissolve involves a series of medicated injections that is claimed to melt away unwanted small, localized pockets of fat.  It is also known as mesotherapy, lipolysis, injection lipolysis or lipostabil.

The ingredients used in lipodissolve vary depending on the physician and the area being treated.  Common ingredients include a chemical cocktail of phosphatidylcholine | deoxycholate (PCDC), multivitamins, alpha lipoic acid (ALA), plant extracts and other enzymes.

Phosphatidylcholine is a soybean extract; deoxycholate is a bile derivative. Phosphatidylcholine is FDA-approved to break down blood fats that may increase the risk of heart disease. It is not approved for injection or any other purpose.

Sometimes, other ingredients are added, such as non-steroidal anti-inflammatory medications, antibiotics and hormones in the cocktail.

Part of the problem, is that there is no standard ingredient list. Many of the individual ingredients are not FDA cleared on their own, much less, as part of an injectable chemical mix.

For those who participate in lipodissolve, a doctor injects the medicated mixture into unwanted fat layers and connective tissue. The injection is done awake, usually with no anesthesia. The medication is supposed to initiate a chemical reaction and physiologic response to dissolve localized areas of fat.

Benefits are supposed to be seen within 3 weeks of treatment and several treatments are recommended 4-6 weeks apart for a series of treatments. Down time is reported as none.

Selling points for mesotherapy are:

  • A non-surgical alternative to liposuction
  • A series of minimally invasive injections that dissolve fat with less cost and no down time

However, there are potential problems:

  • Lipodissolve is not FDA approved.
  • The benefits and safety profile are not established.

The American Society for Aesthetic Plastic Surgery (ASAPS) is currently studying the effectiveness and safety of the procedure.

Presently, neither the ASAPS nor the American Society of Plastic Surgeons (ASPS) recommends the use of lipodissolve or mesotherapy.

ANVISA, the Brazilian equivalent of the FDA, has banned the use of phosphatidylcholine-based injectable products  because they have never been approved for cosmetic use.

Health Canada, the Canadian equivalent of the FDA, has ordered physicians to stop marketing and stop administering these types of products to patients.

For all these reasons, lipodissolve or mesotherapy is not recommended at this time.

We hope you found this page educational and helpful.

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